AIHA or IMHA ... Hemolytic Anemia:  How would you feel, if you were affected? Tired and grouchy and
 

Any of these symptoms of hemolytic anemia  * acute exposure
Chills (advance fatigue)
Fatigue 
Pale color 
Shortness of breath (advance fatigue)
Rapid heart rate 
Yellow skin color (jaundice) 
Dark urine (indicative of blood in urine - never dismiss this! Stop exposure immediately!)
Enlarged spleen

 

Very HIGH WBCs (advance fatigue)

 
LOOK at the red blood cells

This fatigue is caused by exposure to 2-butoxyethanol

www.valdezlink.com/same.htm

www.valdezlink.com/pages/jaundiceandfatigue.htm .... copy & fax or e-mail to your doctor: 
2 pages only ... ending with :
 
AUTOAGGLUTINATION
    In severe cases of immune mediated hemolytic anemia, the immune destruction of red cells is so blatant that the red cells clump together (because their antibody coatings stick together) when a drop of blood is placed on a microscope slide. Imagine a drop of blood forming not a red spot but a yellow spot with a small red clump inside it. This finding is especially for boding.
     
    spikes RBCs?    *
LEUKEMOID REACTION
    Classically, in IMHA the stimulation of the bone marrow is so strong that even the white blood cells lines (which have very little to do with this disease but which also are born and incubate in the bone marrow along side the red blood cells) are stimulated. This leads to white blood cell counts that are spectacularly high.
 
COOMB'S TEST (ALSO CALLED A "DIRECT ANTIBODY TEST")
This is a test designed to identify antibodies coating red blood cell surfaces.  This test is the current state of the art for the diagnosis of IMHA but, unfortunately, it is not as helpful as it might seem.  It can be erroneously positive in the presence of inflammation or infectious disease (which might lead to harmless attachment of antibody to red cell surfaces) or in the event of prior blood transfusion (ultimately transfused red cells are removed from the immune system). The Coomb's test can be erroneously negative for a number of reasons as well. If the clinical picture fits with IMHA, often the Coomb's test is skipped.
 
SPHEROCYTES

    Spherocytes are special red blood cells produced when a red blood cell is not complete removed by the spleen. The spleen cell “bites off” only a portion of the red cell leaving the rest to escape back to the circulation.

    A normal red blood cell is concave on both sides and disc like in shape. It is slightly paler centrally than on its rim. After a portion has been bitten off, it re-shapes into a more spherical shape with a denser red color. The presence of spherocytes indicates that red blood cells are being destroyed.

 

http://www.marvistavet.com/html/body_imha.html
  http://www.valdezlink.com/re/msn/avoid2beforhealth-mm/findanemiaforproof.htm

 

  1. Immune Mediated Hemolytic Anemia

    Jan 30, 2005 ... IMHA recovery. Q: Dear Dr. Mike, My dog is suffering with AIHA. .... The blood work indicated a very high white cell count and her red blood ...
     

 
 

  1. Canine Autoimmune Hemolytic Anemia (AIHA & IMHA) Vetnet discussion ...

     
    High Platelets/Aspirin/Med Reductions · High Reticulocyte count · High SGPT in 3 yr old Yorkie · High White Blood Cell Count - Could It Be AIHA? ...
    www.vetnet.co.uk/forum/

 
 

  1. Immune-mediated hemolytic anemia, autoimmune hemolytic anemia ...

     
    Some dogs with IMHA have marked increases in their white blood cell counts. ... the condition is often referred to as autoimmune hemolytic anemia, or AIHA. ... figure may be as high as 80 percent for the most severely affected dogs. ...
    camboro.orbglobaldesigns.com/.../immunemediated-hemolytic-anemia-autoimmune-hemolytic-anemia-imha-aiha/

Quote:  http://camboro.orbglobaldesigns.com/encyc/canine/immunemediated-hemolytic-anemia-autoimmune-hemolytic-anemia-imha-aiha/

 
 

  1. IMHA

     
    Mar 18, 2008 ... IMHA red blood cells. Red blood cells are coated with Y-shaped antibodies .... This leads to white blood cell counts that are spectacularly high. .... Both have been temporally associated with the development of AIHA. ...
    www.marvistavet.com/html/body_imha.html
 

  1. FIND the ANEMIA of CFS, FM, CFIDS & you will have the proof that 2 ...

     
    Aug 11, 2008 ... A clue to this anemia is very elevated white blood cell counts ... of which the FATIGUE / ANEMIA ... is IMHA or AIHA. To find the fatigue, ...
    www.valdezlink.com/re/msn/...mm/findanemiaforproof.htm
IMHA is a very serious disease associated with a high mortality rate. Sadly, many dogs have succumbed. Several pet owners have used these sad events to create outstanding informational web sites on IMHA in tribute and to help others. We have found these site especially noteworthy and recommend them highly:

www.cloudnet.com/~jdickson/

www.peppypaws.com/LillisLegacy.html