note: English is not my native language.

I have been diagnosed CPEO (Chronic progressive external ophthalmoplegia). The main symptom is the progressive paralysis of the extra ocular muscles which, in turn, causes droopy eyelids, double vision and blurred vision. In its more severe form, it is also possible to show limb weakness, excersise intolerance,cardiac problems, renal failure and liver failure.

Mitochondrial myopathy, the general term for a group of related diseases, including CPEO, is usually caused by a defect in the mitochondrial DNA, causing mitochondrial malfunction and a myriad of diseases and symptoms.

As of today, there is not effective treatment for this disease.

Some doctors recommend the so-called "mitochondrial cocktail", which is a group and vitamins and enzymes that, in some cases, seem to improve patient´s conditions. I have been searching during the last month or so and I have found at least 3 different formulations. The compounds are roughly the same in all of them. For example,

Coenzyme Q10 (CoQ10) 50-200 mg three times daily (although some patients with primary CoQ10 deficiency have taken up to 1000 mg three times daily)
L-carnitine 300-1000 mg three times daily
Thiamine (vitamin B1) 50-200 mg daily
Riboflavin (vitamin B2) 50-600 mg daily
Vitamin C 100-400 mg daily (usually divided into 2-3 daily doses)
Vitamin E 200-1200 IU daily
Vitamin K3 5-80 mg daily
Folate 1-10mg daily
Alpha-lipoic acid up to 400mg three times daily
Creatine monohydrate 5-10 grams daily
Idebenone 45-360 mg three times daily (Sometimes used instead of coenzyme Q10)

Translating this to LE products I have come to this mix:
1. LE Mix
2. Mitochondrial Booster
3. Super ubiquinol
4. Creatine Powder micronized

Do you think is this the right mix ?
Do you have more info on CPEO that I could read ?

Maybe this is a good candidate formulation for a new LE product 

Thanks., LG