Discovered in 1872 & by 100 years later was thought to be autoimmune.  Huntington's disease is a disorder passed down through families in which nerve cells in the brain waste away, or degenerate. Huntington's disease is caused by a genetic defect on chromosome #4. The defect causes a part of DNA, called a CAG repeat, to occur many more times than it is supposed to. Normally, this section of DNA is repeated 10 to 35 times. But in persons with Huntington's disease, it is repeated 36 to 120 times.   In a TV show there was a grandma and her son that came down with it & died:  his sons each came down with it.  There was first paranoia; then memory loss, then personality changes & serious anger outbursts and violence; suicidal tendencies. and then wasting away until death.
Huntington's disease is a disorder passed down through families in which nerve cells in the brain waste away, or degenerate.

Other Names

Huntington chorea

Causes

American doctor George Huntington first described the disorder in 1872.

Huntington's disease is caused by a genetic defect on chromosome #4. The defect causes a part of DNA, called a CAG repeat, to occur many more times than it is supposed to. Normally, this section of DNA is repeated 10 to 35 times. But in persons with Huntington's disease, it is repeated 36 to 120 times

 

Huntington's Disease (HD)
Dozens of News Articles: Research, Treatment, Prevention, Caregiving.
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Huntington's Disease

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Early Investigations of HD and Autoimmunity, 1973-1978
A quite different avenue of research approached Huntington's as an autoimmune disease. Within a year or two after the Columbus symposium, Dad had hired ...
www.hdlighthouse.org/see/immune/history.htm


Harvard Medicine Huntington's Disease

Discovery could shed light on how immune system tolerance is lost with diabetes, huntington's disease and other autoimmune illnesses. ...
hms.harvard.edu/public/disease/huntingtons_disease..
http://hms.harvard.edu/public/disease/huntingtons_disease/focus_huntingtons_disease.html.


HD Theory of Everything
Huntington's disease (HD) is dominant disorder caused by an expansion of .... Treatments that are effective for autoimmune diseases may be effective for HD. ...
hdlighthouse.org/see/immune/immune.htm
http://hdlighthouse.org/see/immune/immune.htm


Biologists Link Huntington's Disease To Health Benefits In Young

Huntington's strengthens the ... Huntington's disease. Tumor suppressor gene ... than those without Huntington's to suffer from autoimmune diseases. ...
http://www.sciencedaily.com/releases/2007/09/070925130029.htm


Autoimmunity Reviews : Xenobiotic-induced autoimmunity and protein ...

Despite of the high prevalence of rheumatic autoimmune diseases, ..... deficiencies in dopamine signaling in presymptomatic Huntington's disease mice, Proc. ...

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6W8V-4F1GN4G-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=56dc9da28dc115bf5439faa1926d73ee

 

 
Autoimmune Pancreatitis: Inflammatory Pancreatic Disease
Until 1995, when autoimmune pancreatitis was first described, pancreatitis was considered a ... huntington's disease. intestinal illness. kidney disease ...
http://autoimmunedisease.suite101.com/article.cfm/autoimmune_pancreatitis
 

Autoimmune Pancreatitis
Inflammatory Pancreatic Disease

The pancreas is an endocrine gland situated in the abdominal cavity that helps regulate blood glucose levels and assists with the digestion of fatty lipids. Inflammation of the pancreas, which is known as pancreatitis, has traditionally been associated with alcohol abuse. However, in 1995 researchers first described a form of chronic pancreatitis associated with autoimmune manifestations. Today it's known that about 5-6 percent of all cases of chronic pancreatitis are autoimmune in nature. And according to recent reports, the incidence of autoimmune pancreatitis appears to be rising, particularly in Japan, Europe, the United States, and Korea.
Autoimmune pancreatitis is considered a benign disorder because patients typically respond favorably to treatment with corticosteroids. Autoimmune pancreatitis is also known by other names including lymphoplasmacytic sclerosing pancreatitis with cholangitis, idiopathic duct destructive pancreatitis, primary inflammatory pancreatitis, non-alcoholic duct destructive chronic pancreatitis, pseudotumorous pancreatitis, tumefactive pancreatitis, and destructive pancreatitis depending on the specific tissue changes found on biopsy or the predominant and accompanying symptoms.
Who Is Affected


Read more: Autoimmune Pancreatitis: Inflammatory Pancreatic Disease - http://autoimmunedisease.suite101.com/article.cfm/autoimmune_pancreatitis#ixzz0CQVcLJVT

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