anemia. Occurs when the body produces antibodies that coat
red blood cells.
hemolytic anemia, the body produces
autoantibodies to red blood cell membrane proteins. (size?
||Thickening of the
blood caused by Immune System
disease is an acquired autoimmune hemolytic anemia due to an
autoantibody usually directed against the I antigen on red
Cold Agglutinin - a particular type of hemolytic
|Porphyria is a metabolic
problem that is thought to be hereditary; however,
could be chemically induced. Difficulty
in making heme, which is the primary component of hemoglobin
in red blood cells. Their lab tests reveal abnormal activity
in one or more of the eight enzymes involved in heme
production. Since most heme is made in the bone marrow,
these "disorders of porphyrin metabolism" are
usually found there or in the liver.
||Pernicious anemia can be
caused when autoantibodies are formed against intrinsic factor which
is needed for vitamin B12 absorption.
||red blood cell
production outside the vertebrae. Red blood cells are derived
from the stem cells in the bone marrow throughout the body.
When individuals become severely anemic, there is not enough
space in the ctive bone marrow to produce hemoglobin, and the
body begins to make blood outside the bone marrow: in the
spleen, liver, and sometimes outside the vertebrae, which can
compress the spinal cord, leading to
this mean abnormal peripheral blood tests - and not showing up
Would this be
an advance stage of autoimmune hemolytic anemia?
increasing recognition that FM and CFS may be autoimmune in
David Moskowitz ("symptoms of CFS and FM most
resemble the flu")
2-butoxyethanol should be suspect for causing
include: Moderate to severe aching and stiffness in
the muscles in your hips, thighs, shoulders, upper arms
and neck ...
palmitoyltransferase II deficiency CPT2 deficiency
is the only gene associated with CPT
Induction of an
autoimmune reaction (e.g., cyclosporine,
Could also be brought on by exposure to glycol ether.
Carnitine palmitoyltransferase II deficiency is a
metabolic disorder characterized by an enzymatic defect
that prevents long-chain fatty acids from being
transported into the
mitochondria for utilization as an energy source.
The adult myopathic form of this disease was first
characterized in 1973 by DiMauro and DiMauro.
It is the most common inherited disorder of lipid
metabolism affecting the skeletal muscle of adults.
CPT II deficiency is also the most frequent cause of
Symptoms of this disease are commonly provoked by
prolonged exercise or periods without food. Can see
symptoms of weakness / deep joint pain / chest pains.
Fatty Acid Oxidation Disorders[PDF]
Because No flu shot!
or similar chemicals cause autoimmune metabolic issues -
||Only shows up in
the group of pregnant woman or just after child birth.
may be caused by an autoimmune reaction,
in which the body attacks its own tissues.
encephalomyelitis (EAE) mediated or
prevented by T lymphocyte lines directed against diverse
antigenic determinants of myelin basic protein.
Acquired resistance to EAE
is directed by the receptor specificity of the
autoimmune anti-BP T cells.
Disease (can happen with the advanced AIHA, usually
Lungs filling with fluid
Do you have FATIGUE?
VERY HIGH WHITE BLOOD CELL
autoimmune disease that damages sensory and motor
nerves," Dr. Armond Goldman, an emeritus professor
in the Department of Pediatrics at UTMB
which struck Franklin Delano Roosevelt (FDR) in 1921 was not
caused by poliomyelitis, as has been universally assumed by
physicians and historians, according to researchers from the
University of Texas Medical Branch (UTMB). They believe that
the most likely cause of FDR's paralysis was Guillain-Barré
did Pres FDR die of?
Chronic Inflammatory Demyelinating
closely related to Guillain-Barre syndrome and it is
considered the chronic counterpart of that acute disease.
* aka Autonomic
Dysfunction, Familial Dysautonomia, Riley-Day Syndrome
Dysautonomia refers to a disorder of autonomic nervous
system (ANS) function. Most physicians
view dysautonomia in terms of failure of the sympathetic
or parasympathetic components of the ANS, but
dysautonomia involving excessive ANS activities also can
occur. Dysautonomia can be local, as in reflex
sympathetic dystrophy, or generalized, as in pure
autonomic failure. It can be acute and reversible, as in
Guillain-Barre syndrome, or chronic and progressive.
Several common conditions such as diabetes and
alcoholism can include dysautonomia. Dysautonomia also
can occur as a primary condition or in association with
degenerative neurological diseases such as Parkinson's
disease. Other diseases with generalized, primary
dysautonomia include multiple system atrophy and
familial dysautonomia. Hallmarks of generalized
dysautonomia due to sympathetic failure are impotence
(in men) and a fall in blood pressure during standing
(orthostatic hypotension). Excessive sympathetic
activity can present as hypertension or a rapid pulse
Sclerosis: The 'Polio' of the 90s
is generally considered an auto-immune disease, an allergic
reaction to oneself that eats away at the myelin sheaths
wrapped around nerve fibers. Sclerosis is the medical term for
lesion, and in MS multiple lesions form on the myelin, which
is akin to the plastic insulation surrounding electrical
wires. The myelin becomes inflamed and literally begins to
fray, short-circuiting nerve signals and leading to the
disease's physical and neurological symptoms. Good diet
'gulf war syndrome' vets have MS
||Is this what the
news reporter in Iraq died of? Is this what more
people die of than AIDS and another ailment combined?
Buerger's Disease – Types of Vasculitis
Thromboangiitis obliterans (Buerger's disease)*
Thromboangiitis obliterans is a rare disease in
which blood vessels of the hands and feet become
blocked. Symptoms: Hands or feet may be pale, red, or
bluish; Hands or feet may feel cold; Pain in the hands
and feet Acute,...
for Anti-phospholipid antibodies [aCL and LA]
of the things
that happened to 'gulf war syndrome' vets
is a rapidly progressive neuromuscular disease caused by
the destruction of nerve cells in the brain and spinal cord.
This causes the loss of nervous control of voluntary muscles,
resulting in the degeneration and atrophy of the muscles.
Eventually the respiratory muscles are affected which leads to
death from an inability to breathe."
there be a glyconutrient trial for ALS?
Many disorders that affect the
nervous system are autoimmune in nature, meaning they occur
when the body’s immune system mistakenly attacks its own
tissues. Microglia, immune system cells found in the nervous
system, appear to play a role in ALS. None of the treatments
used for other autoimmune diseases has been effective
syndrome (APS or APLS)
syndrome (APS or APLS) or antiphospholipid antibody syndrome -
found in recurrent pregnancy loss
Headaches? Hypothalamus headaches?
headaches be autoimmune?
|Good Pasture's Syndrome
particular autoimmune issue against kidneys
Failure - A
||Focal segmental glomerulosclerosis (FSGS)
describes scarring in scattered regions of the kidney
complication of kidney disease, the nephrotic syndrome is a
specific collection of signs and symptoms caused by the loss of
large amounts of protein from the blood into the urine.
Those with nephrotic syndrome are at high risk for end-stage
kidney failure. Once a kidney fails, survival is dependent upon
either dialysis or a kidney transplant. Edema or swelling
in the legs and feet is a common complaint.
|Gall stones ... Kidney stones later on
||Early on with exposure to glycol ether
you see gall stones; 10-15 years later: kidney
stones; all part of autoimmune metabolic
Pneumonia? or Pulmonary Edema
Pulmonary edema may 'look like' pneumonia, but suspect
instead an autoimmune issue in which the lungs fill up
Sarcoidosis is a
relatively rare autoimmune disease that can affect the skin,
lungs, heart, brain and nervous system, eyes and other organs.
In sarcoidosis, the
immune system starts to attack the body's own tissues, forming
small lumps called granulomas. These are like small scars that
interfere with the normal function of the organ attacked by the
||Grouped with autoimmune issues.
Look it up.
is a regulator of the immune system. Many specialists believe
that baldness is an autoimmune disease - a balding person's
own blood cells are recognizing hair as foreign proteins...
Polyglandular autoimmune syndromes (PAS) are a group of
disorders in which multiple endocrine glands make
insufficient amounts of hormones. MayoClinic definition
Autoimmune polyendocrine syndrome type1
Autoimmune polyendocrine syndrome (APS1,
APS2) · Carcinoid syndrome · Multiple endocrine
neoplasia (1, ...
Transfusion-associated graft versus host
polyglandular syndrome type I (APS1,
also called APECED) is a rare autosomal recessive disorder
that maps to human chromosome 21
At the end of 1997,
researchers reported that they isolated a novel gene, which
they called AIRE (autoimmune regulator). Database searches
revealed that the protein product of this gene is a
transcription factor - a protein that plays a role in the
regulation of gene expression.
autoimmune syndromes (PGA) are a group of disorders in which
multiple endocrine glands make insufficient amounts of
hormones. The endocrine glands include the pituitary,
thyroid, parathyroid and adrenal glands.
PGA, the immune system mistakenly attacks the endocrine
Signs and symptoms depend on
which glands are affected. A doctor may make a diagnosis by
blood tests, which measure hormone output by the affected
glands. There is no cure for this disease. Treatment is
directed at managing the signs and symptoms and usually
includes hormone replacement therapy.
(LNS) also known as Nyhan's syndrome, Kelley-Seegmiller
syndrome and Juvenile gout
by a deficiency of the enzyme hypoxanthine-guanine
phosphoribosyltransferase (HGPRT), produced by mutations
in the HPRT gene located on (the) X chromosome. The
HGPRT deficiency causes a build-up of uric acid in all
body fluids. This results in both hyperuricemia and
hyperuricosuria, associated with severe gout and kidney
problems. Neurological signs;
with autoimmune issues present also
must have damaged X chromosome
(listed among autoimmune disorders)
Marfan syndrome is a rare
connective tissue disorder that affects many organ
systems, including the skeleton, lungs, eyes, heart, and
blood vessels. Connective tissue holds body tissues
together and provide support for many structures in the
body. In Marfan syndrome, there is something wrong with
the chemical make-up of the connective tissue. This can
result in problems with the eyes, blood vessels, heart,
spine, and lungs.
What causes 'charlie horses?'
Suspect something autoimmune
"A charlie horse is pain caused by
cramped muscles. Experts have long disagreed about the
causes of sore muscles. Because
nerve cells are situated in the fascia, i.e. the sheath
of connective tissue outside the muscles....
nerve cells and on the muscles blood vessels, and this
pressure is experienced as pain. What Causes Muscle
Cramps? The situations that are likely to cause 'charlie
horse' have one thing in common: incomplete muscular
ITP is the
destruction of "thrombocytes" (clotting cells) by
the immune system in much the same manner as RBCs are
thrombocytopenic purpura (Platelets)
Other autoimmune issues including diabetes
& spontaneous infertility
Using Accutane has caused
this disease include bruising; excessive bleeding following
trauma, at surgery, or during estrus; or
in the urine
Before ITP can be diagnosed,
many more common diseases must be ruled out. These include,
but are not limited to, warfarin poisoning, various clotting
disorders (hemophilia, Von Willebrand's disease), bladder or
prostate infection or cancer, and intestinal parasites. A CBC,
platelet count, and clotting profile are needed. A bone marrow
biopsy is helpful as well, and a Coomb's test may be run if
other autoimmune diseases are suspected. (Coomb's test is
Transfusion of fresh whole
blood or of platelet-rich plasma can be helpful in ITP
may also be
used to treat immunological diseases other than
deficiencies. For example, in immunological thrombocytopenia purpura, the patient's antibodies attack his or her own
platelets, interfering with the blood's ability to clot.
Gamma globulin injections are useful in treating this
condition, though the mechanism by which they work is not
fully understood. The injections may cause the spleen to
ignore signals to destroy the antibody-tagged platelets, or
they may cause the malfunctioning gamma globulin to degrade
at an increased rate. In any case, the extra gamma globulin
counteracts the malfunctioning antibodies that attack
platelets and allows the platelets to thrive."
||If a teratogen chemical causes
autoimmune issues; then maybe parents harmed by it are at
risk for birth defects in their children (also autoimmune?)
& all organic solvents,
pesticides, neurotoxins, teratogens, poisons.
2-butoxyethanol is all of
||NIDS = Neuro Immune Dysfunction Syndromes
||ADEM = Immune Mediated disease of the brain
A study & a probable cause
|I have an
autoimmune disease called "hashimotos thyroiditis"
I no longer have a thyroid, it was removed due to cancer.
hoping that someone here has learned a lot about the
is one of my problems, but not at the top of the
list.. I guess that the worst thing going on is that I
have (or had) 4 different primary cancers. I also
tested positive for antibodies to both mono and
another similar virus (cytemegalo??) I have an
autoimmune disease called "hashimotos thyroiditis"
only I no longer have a thyroid, it was removed due to
cancer. I am having problems with iron deficiency even
though I've been on iron supplements for a few months
now and I have chronic infections.
immune system is not functioning. I've been tested
for HIV and I don't have it. Any thoughts? Is there
another disease that destroys the immune system that
my docs are missing? I have several docs.. my PC
manager, an oncologist, an endochrinologist a
gynecologist and of coarse a couple surgeons.. none of
them can give me any answers. Each treats the disease
that I'm in their office for, but none seems to have a
clue what is going on to cause all of this.
lymphocytic thyroiditis - may
eventually lead to hypothyroidism
thyroiditis aka "Hasa Moto's" disease. (Pre
hypothyroid but will be eventually since the thyroid is
producing more than normal hormones to supplement those
hormones being killed off by the autoimmune disease) The
thyroid will eventually burn itself out.
Hypothyroidism may be a
precursor to kidney stones starting up
||The cause of
virtually all cases of low thyroid is not so much a faulty
thyroid gland, as it is an over-zealous immune system. As
strange as it might seem, common low thyroid is a mild immune
system illness in which the immune system wrongly attacks the
innocent thyroid gland
|Graves 's disease
||Graves 's disease is
associated with auto-antibodies to thyroid stimulating hormone (TSH)
'autoimmune' issues -
body's immune system attacks its own digestive tract. Gluten
Intolerance. It happens when sufferers eat anything
containing gluten, which is found in grains like wheat, barley
and rye. Sufferers report 'abdominal cramping, abdominal pain,
fatigue.' The majority of
children with CD have what's called "failure to thrive:" lack of
growth of weight, and sometimes height as well. Most have
diarrhea, and/or vomiting
are these two conditions associated?
Dermatitis herpetiformis (DH) is an intensely
eruption. A chronic inflammatory disease that produces red
(erythematous), raised (papular), small or large blisters
(vesicles or bullae) that burn and itch
intensely. Dermatitis herpetiformis develops suddenly, lasts
for weeks to months, and may be associated with digestive
diseases (such as Celiac disease).
hepatitis (CAH), or autoimmune hepatitis, is a chronic
inflammatory autoimmune disease of the liver. It usually
occurs by itself, but it can coexist with other autoimmune
diseases, such as systemic lupus or APL syndrome.
differentiates autoimmune hepatitis from other types of CAH is
the presence of autoantibody markers, which may vary in titer
with disease activity.
Syndrome? (or autoimmune hypothalamus?)
||Around 1990, Dr.
Dennis Wilson identified a condition in which the thyroid
tests are in the ‘normal’ range but patients have
and many symptoms suggestive of hypothyroidism.
The old name for this condition was Euthyroid Sick Syndrome.
Dr. Wilson defined it more clearly, including the role of
Reverse T3 (RT3). He called it Wilson’s Syndrome and
developed a therapeutic regiment that helps many sufferers.
His pioneering work brilliantly recommends the use of slow
release T3 as opposed to the quick release.
Addison's disease is an uncommon autoimmune disease,
characterized by chronic and insufficient functioning of the
outer layer of the adrenal gland. The adrenal glands are
located atop each kidney and produce vital glucocorticoid
hormones. Because of this chronic under-functioning of the
adrenal glands, persons with Addison's disease have a
deficiency in the production of glucocorticoid hormones.
Glucocorticoid hormones are involved in how the body utilizes
and stores carbohydrates, protein, fat and blood sugar.
nodosa is a rare autoimmune disease (immune system attacking
its own body) characterized by spontaneous inflammation of the
arteries (arteritis) of the body. Because arteries are
involved, the disease can affect any organ of the body. The
most common areas of involvement include the muscles, joints,
intestines (bowels), nerves, kidneys, and skin. Poor function
or pain in any of these organs can be a symptom. Poor blood
supply to the bowels can cause abdominal pain, local bowel
death, and bleeding. Fatigue, weight loss, and fever are
2-4 million sweat glands that are used
by our nervous system to cool off the body and keep it
within a constant and acceptable temperature. When the
sweating process exceeds its normal production, we are
dealing with the phenomenon called hyperhidrosis.
The hypothalamic preoptic sweat center is located in the
brain and it sends commands through the brain stem and
medulla to the innervations of the sweat glands. The
nerves enter the spinal cord and synapse in the
anterolateral cell column of the spinal cord. Neurons
then exit the spinal cord and enter the sympathetic
ganglia found in the chest and from there they supply
the upper limbs. A hyperactive sympathetic nervous
system is believed to be responsible for hyperhidrosis
or excessive sweating." http://www.hyperhidrosis.us/
action on Gamma
globulin, virus-related antigens)
|Some young people
Valdez oil spill cleanup have come down with this -
Was it the 'cleanup chemical?'
this info to your doctor
fingers curl in over time. Ask, "Is it an AUTO-IMMUNE
DISEASE?" Some think it's genetic; hmm, it does appear
to be autoimmune from all the studies that link it
combination of rheumatoid arthritis, splenomegaly, leukopenia,
pigmented spots on lower extremities, and other evidence of
hypersplenism (anemia and thrombocytopenia). (From Dorland,
Multicentric reticulohistiocytosis: An
autoimmune systemic disease
2010 ... However, it can be
assumed that cellular and/or cytokinic
autoimmune mechanisms could induce the activity of
||Gout is caused by buildup of uric acid in the body. When uric acid levels rise in the body, it crystallizes
and causes sharp needlelike pain, particularly in the toes
and feet. The immune system then attacks the crystals and causes pain
and swelling. Could this
sometimes be part of
autoimmune metabolic problem?
is a type of arthritis that results from too much
uric acid in the body. Rather than being flushed by the
kidneys and through the urine, as it normally is, it forms
crystals and deposits in the joints. These deposits give rise
to inflammation of the joints, causing pain, swelling, redness
and tenderness of the area."
patients usually complain of dry eye symptoms, including
burning, itching or foreign body (gritty, sandy) sensation and
accumulation of thick, ropy secretions along the inner canthus
of the eyes; also
in tasting and smelling
disease in which the body's immune system mistakenly attacks
its own moisture producing glands. Sjögren's is one of the
most prevalent autoimmune disorders, striking as many as
4,000,000 Americans. 30% of patients
with rheumatoid arthritis, systemic lupus erythematosus and
systemic sclerosis suffer secondary
syndrome; many with FM (fibromyalgia)
have this syndrome. A chronic inflammatory disorder of
probable autoimmune nature characterized by infiltration of
the exocrine glands, particularly the salivary and lacrimal
glands, by lymphocytes and plasma cells. The classic signs of
the Sjögren’s syndrome, therefore, includes enlargement of
the parotid glands with mucosal dryness manifest by dry mouth
(xerostomia) and dry eyes (xerophthalmia).
- The Autoimmune Response in
Key Discovery ... Hopkins University is related to
the autoimmune response in scleroderma
is not a single disease but is a symptom of a group
of diseases complicated by the abnormal growth of connective
tissue which supports the skin and internal
often associated with scleroderma
include autoimmune diseases, CFS, fibromyalgia, interstial
cystitis, leukemia, MCTD, multiple sclerosis...
on this health issue -
for people to participate - Help with
Also called CREST syndrome or progressive systemic sclerosis
affects the connective tissue. Scleroderma is a serious,
progressive disease that affects the skin and connective
tissue (including cartilage, bone, fat, and the tissue that
supports the nerves and blood vessels throughout the body).
|Occurs when the
immune system causes an inflammatory response in a joint. It
is painful. Sometimes terribly painful
- Ankylosing spondylitis
autoimmune disease which affects collagen structures,
specifically the joints between the vertebrae of the spine...
spondylitis is a progressive autoimmune disease, which causes
inflammation of and arthritic reactions to the spine and large
joints. It involves ankylosing, or hardening, of the ligaments
and tendons where they attach to the bone
Erythematosis (SLE), also known as lupus, a
Trials of Glyconutrients suggest Real Hope
|a CBC (complete
blood count), serum chemistry analysis, and urinalysis are
starting points. The antinuclear antibody test (ANA) has
become the definitive test for diagnosing SLE
1 in 5 patients with
Lupus have “Sticky Blood” and an increased risk of
is a type of immune system disorder known as an autoimmune
disease. ... may refer to it by yet another term, as a
spondyloarthropathy. ..a group of disorders that can cause
inflammation throughout the body, especially in the spine.
the triad of urethritis, conjunctivitis, and arthritis, is a
seronegative spondyloarthropathy (autoimmune damage to the
cartilages of joints)
||is the most
characteristic cardiac manifestation of the autoimmune disease
systemic lupus erythematosus
Lymphoproliferative Syndrome (ALPS)
|ALPS as a disease
of the immune system. The tools used to fight germs turn
against our own cells and cause problems. The word lymphoproliferative
describes the unusually large numbers of white blood cells
(called lymphocytes) stored in the lymph nodes and spleens
|Lymphocytic hypophysitis (LYH)
hypophysitis (LYH) is an uncommon autoimmune disease in which
the pituitary gland is infiltrated by lymphocytes, plasma cells
and macrophages and its function is usually impaired.
hygroma & lymphangioma)
PLEVA, Mucha-Habberman's disease *
with abnormality in immune system: Pityriasis
lichenoides et varioliformis acuta. The T cells get
mixed up and decide to form in the skin, causing the
A rare auto immune disorder;
overactive immune system causes tissue death.
"A disease that
causes tissue to become
necrotic, causing deep ulcers that usually
occur on the legs. When they occur, they can
lead to chronic wounds. Ulcers usually initially
look like small bug bites or
papules, and they progress to larger ulcers.
Though the wounds rarely lead to death, they can
cause pain and scarring. The disease was
identified in 1930. It affects approximately 1
person in 100,000 in the population."
blogger: "Many years ago I was
told I had so much inflammation in my body that it was
actually seen in my blood as well! Also I have thyroid
and anemia problems."
developed a tiny pimple on my forehead that itched. The next
day I woke up and under my eyes were black and blue and my
eyes were slits!
It was diagnosed as a benign
tumor, that never went away and turned into an opened ulcer.
My skin turns beat red and burns like fire. Sweating from
inflammation! I developed this huge ulcerated sore on my
forehead. I have asthma; Osteo in back and knees
They don't know what step to
take next but it can affect your vitals.
- Pyoderma Gangrenosum : Article by J Mark Jackson, MD
"It seems to be an
occurrence with those who have an inflammatory systemic
All of the one's you mentioned above are correct except for
IBS. IBS is not an inflammatory bowel disease. But Chron's
||In its general use
the term "immune mediated" in front of the
description of an illness, such as immune mediated synovitis
or immune mediated hemolytic anemia, means that the immune
system is inappropriately causing a disease process
- naturally occurring antisperm-antibodies (ASA) as a cause of
male infertility; sperm autoimmunization
||In diabetes mellitus,
autoantibodies are formed against insulin receptors.
Inflammatory Pancreatic Disease
There is an
autoimmune metabolic aspect to Autism, and nervous system
dysfunction, too? I suspect glycol ether (often 2-butoxyethanol) exposure for
Suspect for the Cause of Autism
||Lungs fill up with fluid. Different than
pneumonia, but sometimes 'labeled as such'
pregnancy - can't stay pregnant - preterm pregnancies or
spontaneous aborting - For men Spontaneous Infertility - No
Would treatments of gamma globulin help?
|Is there such a thing as autoimmune
|Huntington's Disease (HD)
I suspect it affected many
who fought in the Civil War - some leukeodystrophies have been
traced back to then. (Gunfire fumes in one's eyes?)
|Discovered in 1872
& by 100 years later was thought to be autoimmune.
disease is a disorder passed
down through families in which nerve cells in the brain waste
away, or degenerate.
disease is caused by a genetic
defect on chromosome #4. The defect causes a part of DNA, called
a CAG repeat, to occur many more times than it is supposed to.
Normally, this section of DNA is repeated 10 to 35 times. But in
persons with Huntington's disease, it is repeated 36 to 120 times. In
a TV show there was a grandma and her son that came down with it
& died: his sons each came down with it. There was
first paranoia; then memory loss, then personality changes & serious anger outbursts and violence;
suicidal tendencies. and then wasting away until death.
|Creutzfeldt Jakob Disease
SSG James Alford
diagnosed in June 2003 with Creutzfeldt-Jakob Disease, a rare and fatal brain
disorder that leads to progressive dementia and neuromuscular
a list of autoimmune diseases,
I don't know why, if it's from a tick bite?